USCGC General Greene (WPC/WSC/WMEC-140), was a 125 ft (38 m) United States Coast Guard Active-class patrol boat, in commission from 1927 to 1968 and the fourth cutter to bear the name of the famous Revolutionary War general, Nathanael Greene. She served during the Rum Patrol, World War II and into the 1960s performing defense, law enforcement, ice patrol, and search and rescue missions.