The Upper West Side is a neighborhood in the borough of Manhattan, New York City, that lies between Central Park and the Hudson River and between West 59th Street and West 110th Street. The Upper West Side is sometimes also considered by the real estate industry to include the neighborhood of Morningside Heights.Like the Upper East Side, the Upper West Side is an affluent, primarily residential area with many of its residents working in more commercial areas in Midtown and Lower Manhattan.