State Route 121 (SR 121) is a state highway in the U.S. state of Virginia. Known as Max Meadows Road, the state highway runs 1.83 miles (2.95 km) from Interstate 77, I-81, U.S. Route 11, and US 52 at Fort Chiswell north to SR 1004 and SR 1006 in Max Meadows in eastern Wythe County.SR 121 is part of a Virginia Byway that continues south along US 52 and west along SR 610 to Wytheville.