State Route 27 (SR 27) is a 90-mile-long (145 km) state highway serving Whitman and Spokane counties, located in the eastern region of the U.S. state of Washington. The highway travels generally north from U.S. Route 195 (US 195) through Pullman, Palouse, Tekoa, and Spokane Valley to SR 290 north of an interchange with Interstate 90 (I-90).