William Wayne “Cotton” Frazier, Sr. (March 5, 1939 – March 11, 2012) was a professional American football center who played four seasons in the American Football League (AFL) from 1962 to 1967. He started with the San Diego Chargers, was traded to the Houston Oilers, then to the Buffalo Bills, and finally to the Kansas City Chiefs in 1966. After winning the AFL championship with the Chiefs that year, he started for them in the first AFL-NFL World Championship Game.