Weird Science was a science fiction anthology comic book that was part of the EC Comics line in the early 1950s. Over a four-year span, the comic ran for 22 issues, ending with the November–December, 1953 issue. Weird Fantasy was a sister title published during the same time frame.Published by Bill Gaines and edited by Al Feldstein, the bi-monthly Weird Science replaced Saddle Romances with the May/June 1950 issue.