West Little Owyhee River is a 63.1-mile-long (101.5 km) tributary of the Owyhee River in the U.S. state of Oregon. The source of the river is at an elevation of 6,508 feet (1,984 m) near McDermitt, while the mouth is at an elevation of 4,373 feet (1,333 m) in the Owyhee Desert. West Little Owyhee River has a 310-square-mile (800 km2) watershed.The river begins east of McDermitt and flows east by Deer Flat and into Louse Canyon.