West Virginia Route 97 is an east–west state highway in the U.S. state of West Virginia. The western terminus of the route is at U.S. Route 52 and West Virginia Route 80 in Hanover. The eastern terminus is at exit 42 of the West Virginia Turnpike (Interstate 64 and Interstate 77) in Mabscott. West Virginia Route 16, which runs concurrent with WV 97 between Sophia and Mabscott, continues north into Beckley on Robert C. Byrd Drive, the right-of-way of both WV 16 and WV 97.