William Henry Trescot (November 10, 1822 – May 4, 1898) was an American diplomatist born in Charleston, South Carolina, on the November 10, 1822. He graduated at College of Charleston in 1840, studied law at Harvard University, and was admitted to the bar in 1843. He was married to Eliza Natalie Cuthbert, whose family had land originally granted by King George II.From 1852 to 1854 he was secretary of the U.S. legation in London.