Wind River Indian Reservation is an Indian reservation made for the Eastern Shoshone tribe of Native Americans in the central western portion of the U.S. state of Wyoming. It is the seventh-largest Indian reservation by area in the United States, encompassing a land area of 3,473.272 sq mi (8,995.733 km²), or land and water area of 3,532.010 sq mi (9,147.864 km²), encompassing just over one-third of Fremont County and over one-fifth of Hot Springs County.