Zuehl is a census-designated place in southwestern Guadalupe County, Texas, United States. It is part of the San Antonio Metropolitan Statistical Area. Located on Cibolo Creek, it lies 14 miles southwest of Seguin. The population was 376 at the 2010 census. Once known as Perryman's Crossing, it was a crossing on the Wood Road, an early road between Gonzales and San Antonio. Wilhem Zuehl bought the land in 1870 and two years later opened a store, from which the community took its name.