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Subject Item
dbpedia:Imatinib
rdfs:comment
Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML).Gleevec is actually the beta crystalline form of imatinib mesilate, the mesylate salt of imatinib.In order to survive, cells need signaling through proteins (signal cascade) to keep them alive.
rdfs:seeAlso
dbpedia:List_of_adverse_effects_of_imatinib
foaf:depiction
n5:svg
dbpedia-owl:atcPrefix
L01
dbpedia-owl:atcSuffix
XE01
dbpedia-owl:bioavailability
98.0
dbpedia-owl:casNumber
152459-95-5
dbpedia-owl:casSupplemental
(mesilate)
dbpedia-owl:chEBI
45783
dbpedia-owl:drugbank
DB00619
dbpedia-owl:fdaUniiCode
BKJ8M8G5HI
dbpedia-owl:iupacName
4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide
dbpedia-owl:pubchem
5291
dbpedia-owl:thumbnail
n7:300