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Subject Item
dbpedia:Methotrexate
rdfs:comment
Methotrexate (INN, AAN, BAN and USAN; /mɛθɵˈtrɛkseɪt/), abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug.It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid.Methotrexate began to replace the more toxic antifolate aminopterin starting in the 1950s.
rdfs:seeAlso
dbpedia:History_of_cancer_chemotherapy
foaf:depiction
n7:svg
dbpedia-owl:atcPrefix
L01
dbpedia-owl:atcSuffix
BA01
dbpedia-owl:bioavailability
60.0
dbpedia-owl:casNumber
59-05-2
dbpedia-owl:chEBI
44185
dbpedia-owl:drugbank
DB00563
dbpedia-owl:fdaUniiCode
YL5FZ2Y5U1
dbpedia-owl:iupacName
(2S)-2-[(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioic acid
dbpedia-owl:pubchem
126941
dbpedia-owl:thumbnail
n5:300