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PEPPSI is an abbreviation for pyridine-enhanced precatalyst preparation stabilization and initiation. It refers to a group of palladium catalysts developed around 2005 by Prof. Michael G. Organ and co-workers at York University, which can accelerate various aminations and cross-coupling reactions. In comparison to many alternative palladium catalysts, PEPPSI-type complexes are stable to air and moisture and are relatively easy to synthesize and handle.
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