. "\"Pilot\"" . . . "Prof. Charles Edward \"Charlie\" Eppes, Ph.D., is a fictional character and one of the protagonists of the CBS crime drama Numb3rs. He is portrayed by David Krumholtz.Dr. Charles Eppes is portrayed as a young mathematical genius and professor of applied mathematics at the fictional California Institute of Science, CalSci (primarily based on Caltech, where some filming and mathematics consulting is done)."@en . "Charles Edward Eppes"@en . . . . . . .