. "American biophysicist" . . . . . . "Isabella Helen Lugoski Karle (born December 2, 1921) is an American x-ray crystallographer. In 1969 she established the structure of venom extracted from South American frogs. This was followed in 1975 with the structure of valinomycin."@en . . "Isabella Helen Lugoski"@en . "1921-12-02Z"^^ . "Isabella Karle"@en . . "1921Z"^^ . "Karle, Isabella"@en .